WELCOME TO 

THE MA LAB!

The Laboratory of Neuroplasticity and Brain Dysfunction, directed by Professor Yao-Ying Ma, studies the pathologic adaptations in diseased brains at multiple levels, including synaptic, cellular, circuit and system levels. The major research directions include developmental alcohol exposure, long persistence of drug craving, and emotional components of neurodegenerative diseases. We employ a diverse range of technical approaches, such as whole-cell patch clamp electrophysiology, optogenetics, chemogenetics, biochemical analyses, single cell staining combined with confocal imaging to examine spine morphology, transgenic model animals, behavioral evaluations such as operant goal-directed or habitual behavior, anxiety-like and depression-like behavioral symptoms. Our general aims are to explore the underlying mechanisms in a more precise way and to reverse aberrant neuronal and synaptic dysfunction. 

Lab News

September 2020

  • Congratulations to Dr. Ma on her new R01  award from NIG.  This is a 5-year grant to explore whether, and how if yes, prenatal alcohol experience facilitates the  Alzheimer's Disease-associated phenotypes. 

 

September 2020

  • Congratulations to our undergraduate research assistant, Victoria Roselli on her 1st-authored paper published in Neuropharmacology!

 

June 2020

  • Welcome to Olivia Lorrinaour Martin joining our lab for her Ph.D. program. 

May 2020

  • Congratulations to our graduate student, Donald Huang, who successfully made his qualifying exam. 

Research Direction 1

CURRENT RESEARCH PROJECTS

Research Direction 3
Neurodegenerative
Diseases
Research Direction 2
Cocaine
Addiction
Research Direction 1
Developmental
alcohol exposure

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